Bears Game Saturday: Bills vs Bears prediction, odds, spread, line, over/under & betting info for Preseason Week 2

Chicago Bears - Credit: Jon Durr-USA TODAY Sports
Chicago Bears - Credit: Jon Durr-USA TODAY Sports /

This Saturday the Chicago Bears will face off against the Buffalo Bills. The Bears will once again be at home with their fans in the stands at Soldier Field. This will be an interesting matchup as fans will get to see Mitch Trubisky return for his “revenge game”.

It seems that fans are still split when it comes to their feelings about Trubisky but with Justin Fields proving himself last week, no one should be concerned about Trubisky any longer. Well, at least not after this game on Saturday. In his first game with Buffalo, Trubisky only attempted two passes, completing one for 10 yards. The Bills won their first preseason game 16-15 versus the Lions, but Trubisky had nothing to do with it.

Justin Fields on the other hand was the main reason the Chicago Bears won their first preseason game versus the Dolphins. Fields started off slow but completed 14 of 20 passes for 142 yards and a touchdown. He added another touchdown on the ground by rushing for 33 yards on five carries. Will we actually see a Fields vs. Trubisky game or will other backups see a vast majority of the reps?

Chicago Bears vs Buffalo Bills Odds for Preseason Week 2

Heading into Saturday’s Week 2 Preseason game, both the Chicago Bears and Buffalo Bills enter the matchup 1-0. Preseason games mean little in the grand scheme of things. As of now, the Bears are favored by what I would consider a significant margin at -5.0 according to the latest odds from WynnBET.

Betting on preseason games is a little more difficult than betting on regular-season games. Too many variables exist in the preseason. We don’t know exactly how many plays a player will see. We don’t know how many carries or targets a player may see. Preseason is just more unpredictable than the regular season. This is why many will only bet the Moneyline during the preseason and leave the spread alone.

The Moneyline is essentially just picking the winner, however, sportsbooks will give you different odds (or payouts) based on which team they believe will win or lose. Currently, WynnBET has the Bills’ odds set at +180 (bet $100 to win $180), while the Bears’ odds are -225 (bet $225 to win $100).

If none of these two odds do anything for you, then your other option is to consider the over/under. WynnBET has set the total over/under for the Bears’ second preseason game at 38.5 with the odds set at -110 for both (bet $110 to win $100). An Individual team over/under for the Bills is set at 16.5 with the over at -120 and the under at -110. The Chicago Bears’ over/under is currently set at 21.5 with the over at -120 and the under at -110.

Odds shift as Chicago Bears rookie quarterback, Justin Fields misses practice with a groin injury

And just like that, the odds have shifted in the Buffalo Bills favor. It is important to note that these odds are very fluid and will adjust and shift for many reasons. In this case, Justin Fields was not a participant at Bears practice today due to a groin injury. With his availability now in question for Saturday’s game, the new odds are as follows.


  • Buffalo Bills: +4.0
  • Chicago Bears: -4.0


  • Buffalo Bills: +170
  • Chicago Bears: -200


  • Over: 38.0 (-115)
  • Under: 38.0 (-115)

Chicago Bears Injury Report vs Buffalo Bills for Preseason Week 2

We will know more as we get closer to Saturday, but the Chicago Bears injury report is somewhat lengthy. Teven Jenkins is still out and who knows what his future holds for the 2021 season. Other notables who are continuing to miss time include Tarik Cohen (PUP), Germain Ifedi (PUP), Ryan Nall (chest), James Daniels (quad) and Robert Quinn (ankle).

The good news is that Artie Burns, Tashaun Gipson and Marquise Goodwin all returned this week.

Chicago Bears vs Buffalo Bills prediction for Preseason Week 2

Matt Nagy is now in his fourth year as the Bears head coach, but due to COVID-19, he is entering year three of the preseason. With 2018 and 2019 under his belt, Nagy has a 3-5 record. Now after the win versus the Dolphins last week, his record is now at a modest 4-5.

Sean McDermott has been the head coach of the Bills since 2017. Without a 2020 preseason, McDermott has a 7-5 record while in Buffalo. Last season though, the team went 4-0 and the last time these two teams met in the preseason was 2018. The Bills won 28-27 by scoring 25 unanswered points in the fourth quarter.

As much as it pains me to say this, taking the Bills +5.0 seems like a no-brainer. The Moneyline seems like the smart move too, seeing that the odds are better for the Bills, but give me Justin Fields over Mitch Trubisky (or whoever else plays more between Jake Fromm and Davis Webb). The Bears should win this one, but it will likely be within five points.

Download the WynnBET App and make your pick here

Chicago Bears next game & schedule:

After the game on Saturday, the Chicago Bears will turn their attention to the Tennessee Titans. The third preseason game is usually the main dress rehearsal. It will be interesting to see how teams handle a shortened preseason though seeing the third game is now the final game.

The final Bears’ preseason game takes place on Saturday, August 28 at 6:00 p.m. CT.

What channel is the Chicago Bears preseason game on this week?

The Bears’ preseason game versus the Bills on Saturday will be broadcast locally on WFLD FOX 32 Chicago.

Chicago Bears vs Buffalo Bills live stream

For those who are looking for streaming options, FuboTV is one of the best options to consider for live sports, especially since they are currently offering a free seven-day trial for new users.

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